Morton's neuroma develops in the plantar digital nerves that run between the long bones (metatarsals) of the foot. These nerves can become irritated from compression and friction trauma of the surrounding tissue when the foot is squeezed by footwear, as the result of inefficient gait patterns, and occupational or recreational foot position. 

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Morton's neuroma commonly occurs between the third and fourth toes on your foot, however, it can occasionally appear between other toe joint spaces. 

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